... understanding life in molecular detail

A Peak of Research Excellence at the University of Leeds

  • The Astbury Centre Welcome to the website of the Astbury Centre for Structural Molecular Biology. The Astbury Centre is an interdisciplinary research centre that brings together around 250 researchers from across the University to understand the molecular basis of life.
  • Major grant This project involves researchers from the University of Leeds and Bristol and three drug discovery organisations. The project is led by Professor Andy Wilson, with Prof Nelson and Dr Edwards. Read more..
  • Andrew Macdonald Andrew Macdonald, who leads a combined virological and medicinal chemistry approach to identify the Achilles' heel of BK virus, a major cause of kidney transplant rejection, presented his work both at the House of Lords and in a recent television interview. Read more ....
  • University Investment The University of Leeds is investing £17 million in a state-of-the-art laboratory for structural biology. The new facility will provide the Centre with instruments for Electron Microscopy and Nuclear Magnetic Resonance that are competitive with the very best in the world.
  • University Investment Our new 950 MHz Bruker nuclear magnetic resonance (NMR) magnet has arrived in the Astbury Biostructure Laboratory on September 29. When fully installed, it will be the most advanced equipment of its type in the UK.
  • The Astbury Conversation The Astbury conversation will bring together leading researchers to discuss the most recent work in structural molecular biology. This unique event will comprise a Symposium, Public Engagement Event and Public Lecture by Nobel Laureate Professor Michael Levitt, FRS. Further details.
  • New mass spectrometers James Ault, Alison Ashcroft and collaborators have taken delivery of two new electrospray mass spectrometers in the Biomolecular Mass Spectrometry Facility, courtesy of BBSRC ALERT14 funding. The instruments have a range of protein and peptide sequencing facilities, and ion mobility 'shape' separation.
  • Bragg bust A new bust of Nobel Laureate and pioneer of X-ray crystallography who was Cavendish Chair of Physics in Leeds from 1909 to 1915 was unveiled in Parkinson Court by Emeritus Prof Alan Watson, FRS, and Director of the Astbury Centre, Prof Sheena Radford, FRS.
  • The Astbury Centre Brochure The Astbury Centre launches a new logo and a brochure highlighting our science, training, equipment infrastructure and outreach activities. Download the new brochure.
    New logo available on the intranet.
  • The Astbury Centre The Centre is named after Prof William Astbury, FRS, one of the pioneers of modern structural molecular biology.
  • Bragg on Braggs Melvyn Bragg presents a history of X-ray crystallography including a contribution from Astbury Deputy Director Thomas Edwards
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The Astbury Centre

The Astbury Centre brings together researchers from across the University - largely from physics, the biological sciences and chemistry - to allow interdisciplinary approaches to be harnessed to understand the molecular basis of life. The Centre has outstanding expertise and research infrastructure in chemical biology, biophysics and all of the major techniques in structural molecular biology. Together, these approaches are combined with analyses of biological function with the ultimate aim of understanding the molecular basis of biological mechanisms in living cells. Our members address major questions associated with biological mechanisms in areas as diverse as membrane proteins; protein folding and assembly; viruses; and motor proteins. The Astbury Centre hosts 4-year PhD programmes funded by the Wellcome Trust and BBSRC that recruit students with the wide range of expertise that may be used to address fundamental biological questions.

Welcome to the Centre

Link to movie welcome from Director
Link to a short movie introducing the Centre

The University of Leeds is investing in 250 new academic fellowships, search all the opportunities at 250greatminds.leeds.ac.uk and search #250greatminds for updates

absl link

Follow our progress as we deliver the Astbury Biostructure Laboratory

Welcome to the Centre

Link to movie welcome from Director

Astbury Centre Brochure

Download the Centre's Brochure

Upcoming seminar

Thursday 03 March 2016
4 pm Chemistry LT B
Dr Christian Ottmann
Eindhoven University of Technology
Structural insights on Small-molecule Stabilization of 14-3-3 Protein-Protein Interactions
Host: Adam Nelson

Useful Links