... understanding life in molecular detail

The DirectorAbout us

The Astbury Centre for Structural Molecular Biology (ACSMB) is an interdisciplinary research centre of the University of Leeds.

ACSMB brings together over fifty academic staff from three faculties - biological sciences, physical sciences (chemistry and physics) and medicine - who share the common goal of understanding life in atomic detail.

ACSMB is a major Centre for research and training in structural molecular biology in its broadest sense, is host to a Wellcome Trust-funded 4-year PhD programme (The Molecular Basis of Biological Mechanisms) and centrally involved in a BBSRC-funded PhD programme (Mechanistic Biology and its Strategic Application). The Centre has outstanding research infrastructure including all of the major techniques for structural molecular biology: X-ray diffraction, nuclear magnetic resonance spectroscopy, electron microscopy and mass spectrometry. The Centre's expertise in structural biology is complemented by expertise in chemical biology, molecular biophysics and cell biology. Together these approaches are combined with analyses of biological function with the ultimate aim of understanding the molecular basis of biological mechanisms in living cells. Our members address major questions associated with biological mechanisms in areas as diverse as membrane proteins; protein folding, protein-protein interactions and assembly; viruses; enzyme mechanism and motor proteins.