Positions
Leeds Research Spotlights and Structures ....
- A Gallery of Astbury Centre Front Page Images
- A Gallery of Structures associated with the Astbury Centre
- In addition to these pictures we have tabulated all the published coordinate sets associated with the Astbury Centre
| A Gallery of Astbury Centre Web Page Images To find further information on the laboratory involved in this work click on the picture or the link | |
 | The structure of ketohexokinase A solved in Prof Simon Phillips' laboratory More information about Prof Simon Phillips and his research interests |
 | Screening for new enzyme activities by directed evolution in Dr Alan Berry's laboratory More information about Dr Alan Berry and his research interests |
 | Single fluorescein molecules imaged with our new TIRF microscope - Prof Alastair Smith More information about Prof Alastair Smith and his research interests |
 | Laser-induced temperature jump to study folding rates of BdpA in the laboratories of Prof Radford and Prof Smith More information about Prof Sheena Radford and her research interests |
 | Gallery of AFM images of T7 polymerase bound to DNA templates - Dr Neil Thomson More information about Dr Neil Thomson and his research interests |
 | Adsorbing membrane vesicles on specially designed electrodes enables electrochemical studies of membrane proteins - Dr Lars Jeuken More information about Dr Lars Jeuken and his research interests |
 | Primary human endothelial cells have cylindrical secretory granules containing the pro-coagulation Von Willebrand Factor (green) with the cell nuclei also shown (blue) - Dr Vas Ponnambalam More information about Dr Vas Ponnambalam and his research interests |
 | A DNA sequence being transformed into a 3D protein structure via in silico prediction algorithms - Dr Martin Parker More information about Dr Martin Parker and his research interests |
 | 3D reconstruction of mono-ubiquitinated actin filaments. Shown are ubiquitinated actin, control actin and the difference map, revealing the ubiquitin. These were calculated from cryo-EM images with a new image processing method. Taken from Burgess et al J Mol Biol 341, 2004. More information about Prof John Trinick and his research interests |
 | Model of the active site of the bacterial nucleoside transporter NupG, showing residues that may be involved in adenosine binding - Prof Steve Baldwin More information about Prof Steve Baldwin and his research interests |
 | Structure of the bacterial nucleoside transporter NupG modelled on the crystal structure of the homologous lactose transporter LacY from Escherichia coli - Prof Steve Baldwin More information about Prof Steve Baldwin and his research interests |
 | Protein-protein interface prediction using machine learning and patch analysis in the laboratory of Dr David Westhead (a) actual homodimeric interface on a coenzyme A reductase (PDB code: 1qax), (b) predicted interface. More information about Prof David Westhead and his research interests |
 | Structure of the anti-depressant drug Tranylcypromine bound to the active site of copper-containing Amine Oxidase (see: Wilmot et al, (2004) FEBS Letters, 576, 301-305) - Prof Simon Phillips. More information about Prof Simon Phillips and his research interests |
 | Structure of the Met repressor MetJ solved in Simon Phillips' and Peter Stockley's laboratories. More information about Prof Peter Stockley and his research interests |
 | Structure of the Mouse major urinary protein. This protein is under study in the labs of Simon Phillips, John Findlay and Steve Homans. More information about Prof Steve Homans and his research interests |
 | Structure of galactose oxidase. This protein is under study in the laboratories of Profs Simon Phillips and Mike McPherson. More information about Prof Mike McPherson and his research interests |
 | Structure of beta-2 microglobulin. Amyloid fibrils formed from ths protein are under study by Prof Sheena Radford and her research group. More information about Prof Sheena Radford and her research interests |
 | Structure of the restriction enzyme BglI solved in Prof Simon Phillips' laboratory. More information about Prof Simon Phillips and his research interests |
 | Structure of the subunit B of Shiga-like toxin under study in Prof Homan's laboratory. More information about Prof Steve Homans and his research interests |
 | Structure of copper amine oxidase under study in Prof Phillips' and McPhersons laboratories. More information about Prof Mike McPherson and his research interests |
 | AFM image of staphylococcal plasmid pC221 mixed with mobilisation accessory protein MobC. Mobilisation of plasmids allows the spread of antibiotic resistance through a bacterial population (Jamie Caryl, Neil Thomson and Chris Thomas. More information about Dr Chris Thomas and his research interests |
 | The structure and function of RNase E, a critical enzyme in RNA turnover are being studied by Dr Kenneth McDowall (see Nature, 347, 1187-1191). More information about Dr Kenneth McDowall and his research interests |
 | Dr Richard Jackson is using a bioinformatics approach to predict protein-protein interactions. More information about Dr Richard Jackson and his research interests |
 | CONGRATULATIONS to Dr Lars Jeuken on being awarded the British Biophysical Society Young Investigator's Award 2006 More information about Dr Lars Jeuken and his research interests |
 | AFM tapping mode scan of a bovine achilles tendon collagen fibril on a silica surface showing the typical banded structure (~67nm) of collagen fibrils
More information about Dr David Brockwell and his research interests |
 | Distribution of the Hepatitis C Virus Core protein in infected human hepatoma cells More information about Prof Mark Harris and his research interests |
 | In silico predictions of amyloidogenic peptides More information about Dr Martin Parker and his research interests |
 | Crystals of RNA binding proteins and cofactors produced in Dr Edwards
laboratory More information about Dr Thomas Edwards and his research interests |
 | The crystal structure of VicRc, the DNA-binding domain of an essential response regulator, compared with PhoB in complex with DNA. More information about Dr Mary Phillips-Jones and her research interests |
 | AFM tapping mode scan of a bovine achilles tendon collagen fibril on a silica surface showing the typical banded structure (~67nm) of collagen fibrils
More information about Dr David Brockwell and his research interests |
 | Collisions between two E. coli RNA polymerases convergently transcribing linear dsDNA templates observed by AFM. This study of an in vitro model for nested genes was undertaken in collaboration with Prof. J. Kirkham and Dr. W. Bonass in the Leeds Dental Institute (see: Crampton et al. 2006, Nucleic Acids Res, 34 (19) 5416). More information about Dr Neil Thomson and his research interests |
 | Structure of the Holliday resolvase T7 Endonuclease 1 bound to a DNA 4-way junction, solved by Jon Hadden in Simon Phillips' lab (see Hadden, J.M., Declais, A-C., Carr, S.B., Lilley D.M.J. and Phillips, S.E.V. (2007)Nature, 449, 621-624)
More information about Prof Simon Phillips and his research interests |
 | Part of the diverse library of molecular frameworks generated by a novel approoach in Prof Nelson's laboratory More information about Prof Adam Nelson and his research interests |
