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Astbury Report 2006

INDEX TO THE 2006 REPORT
The full 2006 report can be downloaded as an 15.8MB pdf file here.
Individual reports can be downloaded as pdf files using the links below
Director's statement for 2006 Download
Alison Ashcroft Mass spectrometry research group & facility
Applications of synthetic organic chemistry to biological problems
Investigating fibril structure and assembly using mass spectrometry
Determining the mechanism of bacterial fibre assembly using non-covalent electrospray ionisation mass spectrometry
Assembly of ssRNA viruses: The role(s) of the package during packaging.
Alan Berry Directed evolution of new enzyme activities
David Brockwell Mechanical unfolding of proteins using dynamic force spectroscopy
Stan Burgess Structural studies of the motor protein dynein
Thomas Edwards Solution structure of the Vts1 SAM domain bound to RNA
John Findlay Lipocalin receptors
Mark Harris Studies on the functions of hepatitis C virus proteins
Studies on the HIV-1 Nef protein
Peter Henderson Electrodes for redox-active membrane proteins
In vitro studies of sensor kinase and response regulator proteins of the Prr two-component signal transduction pathway in Rhodobacter sphaeroides
Julian Hiscox Development of a herpesvirus-based bionanosubmarine
Steve Homans The contributions of backbone protein dynamics and ligand reorientation to the thermodynamics of ligand binding by arabinose binding protein
Contribution of ligand desolvation to binding thermodynamics of ligand-protein interactions
Contributions to the change in heat capacity occurring on ligand-binding to the major urinary protein
The beta2m folding free energy landscape
Lars Jeuken Electrodes for redox-active membrane proteins
Peter Knight Structural studies of the motor protein dynein
Structure and properties of regulated myosin 5
Peter Knowles Two metals are better than one: E. coli amine oxidase
Second co-ordination sphere residues in galactose oxidase: tryptophan 290
Mike McPherson Two metals are better than one: E. coli amine oxidase
Second co-ordination sphere residues in galactose oxidase: tryptophan 290
Recombinant production of peptidic bionanomaterials
Adam Nelson Directed evolution of new enzyme activities
Applications of synthetic organic chemistry to biological problems
Uses of RNA aptamers in molecular biology
Peter Olmsted Theoretical and computational studies of mechanical unfolding of proteins
Emanuele Paci Theoretical and computational studies of mechanical unfolding of proteins
Molecular mechanisms of dextran and pectin extension
Simon Phillips Two metals are better than one: E. coli amine oxidase
Second co-ordination sphere residues in galactose oxidase: tryptophan 290
Structure and function of AhrC, the arginine transcription factor from Bacillus subtilis
The structure of the complex between Bacteriophage T7 Endonuclease I and a synthetic Holliday Junction
Crystal structure of the response regulator VicR DNA-binding domain
X-ray crystallographic analysis of GehD lipase: a potential virulence factor Staphylococcus epidermidis infection
Structure determination of a 59 kDa fragment of the DNA-cleavage domain of topoisomerase IV from Staphylococcus aureus
Uses of RNA aptamers in molecular biology
Assembly of ssRNA viruses: The role(s) of the package during packaging.
Mary Phillips-Jones In vitro studies of sensor kinase and response regulator proteins of the Prr two-component signal transduction pathway in Rhodobacter sphaeroides
Crystal structure of the response regulator VicR DNA-binding domain
Sheena Radford Mechanical unfolding of proteins using dynamic force spectroscopy
Early states during protein folding
Single molecule protein folding and kinetics
Investigating fibril structure and assembly using mass spectrometry
Determining the mechanism of bacterial fibre assembly using non-covalent electrospray ionisation mass spectrometry
The beta2m folding free energy landscape
Molecular mechanisms of dextran and pectin extension
Uses of RNA aptamers in molecular biology
Neil Ranson Assembly of ssRNA viruses: The role(s) of the package during packaging.
David Rowlands Targeting the functions of viral proteins with RNA aptamers
Uses of RNA aptamers in molecular biology
D. Alastair Smith Mechanical unfolding of proteins using dynamic force spectroscopy
Early states during protein folding
Single molecule protein folding and kinetics
Molecular mechanisms of dextran and pectin extension
The design and construction of magnetic tweezers, and the investigation of fibrin clots
Mapping ATP-Dependent Activation at a Sigma54 Promoter
Peter Stockley Applications of synthetic organic chemistry to biological problems
Structure and function of AhrC, the arginine transcription factor from Bacillus subtilis
Uses of RNA aptamers in molecular biology
Bacteriophage and virus-like particles as scaffolds for the fabrication of nano-scale devices.
Viruses and virus-like particles as nanoscale delivery systems on a molecular railroad.
Assembly of ssRNA viruses: The role(s) of the package during packaging.
Mapping ATP-Dependent Activation at a Sigma54 Promoter
Nicola Stonehouse Targeting the functions of viral proteins with RNA aptamers
Investigating the molecular interactions of the phi-29 DNA packaging motor
Assembly of ssRNA viruses: The role(s) of the package during packaging.
Chris Thomas Molecular mechanism of Staphylococcal plasmid transfer
Structure determination of a 59 kDa fragment of the DNA-cleavage domain of topoisomerase IV from Staphylococcus aureus
Neil Thomson Convergent transcription studied at the single molecule level by AFM
The design and construction of magnetic tweezers, and the investigation of fibrin clots
John Trinick Titin
Electron microscopy of intact tissues and cells
Automated electron microscopy with Leginon
David Westhead Bioinformatics applied to protein structure and function analysis, and systems biology
Adrian Whitehouse Identification of the ribonucleoprotein complex required for efficient export of herpesvirus intronless mRNAs
Development of a herpesvirus-based bionanosubmarine
Repressosome formation and disruption regulates the KSHV latent-lytic switch
Andy Wilson Synthesis of alpha-helix mimetics: inhibitors of protein-protein interactions
Astbury Seminars 2006 Download
Astbury Publications 2006 Download