... understanding life in molecular detail

Astbury Report 2009

INDEX TO THE 2009 REPORT
The full 2009 report can be downloaded as an 6.7MB pdf file here.
Individual reports can be downloaded as pdf files using the links below
Director's statement for 2009 Download
Alison Ashcroft Biomolecular mass spectrometry
Characterisation of the Mhp1 hydantoin transport protein
Protein-surface recognition using synthetic agents
Stefan Auer Simulating the self assembly and nucleation of peptides into amyloid fibrils
Steve Baldwin Insights into membrane protein function from molecular modelling
Characterisation of the Mhp1 hydantoin transport protein
Biomimetic production of precise nanomagnetic particles using magnetic bacteria and their biomineralisation proteins
John Barr Repair of essential terminal sequences by a negative stranded RNA virus
Alan Berry Development of LC-MS-MS assays for the directed evolution and characterisation of aldolase enzymes
David Brockwell Unravelling complexity in the energy landscape of proteins
Exploring the folding energy landscape of immunity protein 7
Mechanical response of collagen fibrils measured by atomic force microscopy
Stan Burgess Structural studies of the motor proteins dynein and myosin
Influence of lever structure on myosin 5a walking
Rongjun Chen Responsive biomaterials for medical applications
Lorna Dougan Single molecule characterisation of protein folding and dynamics
Thomas Edwards The molecular basis for cellular asymmetry
Protein-surface recognition using synthetic agents
Colin Fishwick Characterisation of the Mhp1 hydantoin transport protein
Structure based design of inhibitors of human and Plasmodium falciparum dihydroorotate dehydrogenase
Stephen Griffin Targeting viral ion channels for therapy
Studies on hepatitis C virus replication and pathogenesis
NMR solution structure of the hepatitis C virus p7 ion channel
Structural studies of innate immune signalling proteins and viral oncogenes
Sarah Harris Biomolecular mass spectrometry
Mark Harris Targeting viral ion channels for therapy
Studies on hepatitis C virus replication and pathogenesis
NMR solution structure of the hepatitis C virus p7 ion channel
Peter Henderson Biomolecular mass spectrometry
Characterisation of the Mhp1 hydantoin transport protein
Electrodes to study membrane proteins
Activation and inhibition of purified intact membrane sensor kinases involved in virulence and antibiotic resistance in Enterococcus faecalis
Eric Hewitt Fibril fragmentation in amyloid assembly and cytotoxicity
Steve Homans Conformational changes during β2-microglobulin amyloid assembly
NMR solution structure of the hepatitis C virus p7 ion channel
Fibril fragmentation in amyloid assembly and cytotoxicity
Structural investigation of a fibronectintype III domain tandem from A-band titin
Studies on bacterial toxins
Nigel Hooper Proteolysis and protein:protein interactions in neurodegenerative diseases
Biophysics of lipid bilayers
Lars Jeuken Electrodes to study membrane proteins
Peter Knight A stable single alpha-helix can act as a lever in myosin
Influence of lever structure on myosin 5a walking
Andrew Macdonald Structural studies of innate immune signalling proteins and viral oncogenes
Kenneth McDowall The yin and yang of gene expression
Adam Nelson Development of LC-MS-MS assays for the directed evolution and characterisation of aldolase enzymes
Peter Olmsted Biophysics of lipid bilayers
Emanuele Paci Simulations are instrumental in interpreting single-molecule experiments and determine free-energy landscapes of proteins
Arwen Pearson NMR solution structure of the hepatitis C virus p7 ion channel
Structural studies of innate immune signalling proteins and viral oncogenes
Terahertz spectroscopy of single crystal proteins
Studies on bacterial toxins
Mechanistic study of an ADP-dependent kinase
Mary Phillips-Jones Activation and inhibition of purified intact membrane sensor kinases involved in virulence and antibiotic resistance in Enterococcus faecalis
Sheena Radford Biomolecular mass spectrometry
Conformational changes during β2-microglobulin amyloid assembly
Exploring the folding energy landscape of immunity protein 7
Fibril fragmentation in amyloid assembly and cytotoxicity
Towards a structure of β2-microglobulin amyloid fibrils
Mechanical response of collagen fibrils measured by atomic force microscopy
Neil Ranson Studies on bacterial toxins
Sarah S Staniland Biomimetic production of precise nanomagnetic particles using magnetic bacteria and their biomineralisation proteins
Peter Stockley Biomolecular mass spectrometry
Nicola Stonehouse Biomolecular mass spectrometry
Chris Thomas Induced bending of a plasmid origin of replication by its cognate replication initiator protein, RepD, and the helicase PcrA
Neil Thomson Induced bending of a plasmid origin of replication by its cognate replication initiator protein, RepD, and the helicase PcrA
Mechanical response of collagen fibrils measured by atomic force microscopy
John Trinick Shape and flexibility in the titin 11-domain super-repeat
Structural investigation of a fibronectintype III domain tandem from A-band titin
Influence of lever structure on myosin 5a walking
Roman Tuma Structure of self-assembling bacteriochlorophyll nanostructures
Bruce Turnbull Studies on bacterial toxins
Stuart Warriner Development of LC-MS-MS assays for the directed evolution and characterisation of aldolase enzymes
Protein-surface recognition using synthetic agents
Michael Webb Mechanistic study of an ADP-dependent kinase
Protein-surface recognition using synthetic agents
Adrian Whitehouse Identification of the ribonucleoprotein complex required for efficient export and translation of herpesvirus intronless mRNAs
Repressosome formation and disruption regulates the KSHV latent-lytic switch
Andy Wilson Biomolecular mass spectrometry
Protein-surface recognition using synthetic agents
Dejian Zhou A pH-driven, fast-responding DNA hydrogel
Astbury Seminars 2009 Download
Astbury Publications 2009 Download