... understanding life in molecular detail

Astbury Report 2010

INDEX TO THE 2010 REPORT
The full 2010 report can be downloaded as an 6.7MB pdf file here.
Individual reports can be downloaded as pdf files using the links below
Director's statement for 2010 Download
Alison Ashcroft Biomolecular mass spectrometry
Proteomimetics as potential anticancer agents
Stefan Auer Phase behaviour and transitions of peptides and proteins
Steve Baldwin Molecular mechanisms of nutrient and drug uptake by cells
Exploring protein folding energy landscapes
Biomimetic production of precise nanomagnetic particles using magnetic bacteria and their biomineralisation proteins
John Barr Diverse aspects of negative stranded RNA virology
Alan Berry Novel enzymes based on the N-acetyl neuraminic acid scaffold
David Brockwell Exploring proteins and their complexes using force
Biophysical theory of lipid bilayers and proteins
Exploring protein folding energy landscapes
Stan Burgess Structural studies of the motor proteins dynein and myosin
Lorna Dougan Molecular self-assembly in a model amphiphile system
Thomas Edwards The structure of the Pumilio homology domain of murine Pum2
Proteomimetics as potential anticancer agents
John Findlay Development of small- molecule tools to probe or inhibit biomolecules and their complexes
Colin Fishwick Development of small- molecule tools to probe or inhibit biomolecules and their complexes
Stephen Griffin Viroporins and enveloped virus assembly as antiviral targets
Studies on hepatitis C virus replication and pathogenesis
Mark Harris Viroporins and enveloped virus assembly as antiviral targets
Studies on hepatitis C virus replication and pathogenesis
Peter Henderson Biomolecular mass spectrometry
Structure-activity relationship of the bacterial galactose-H+ symport protein: homologue of the human GLUT transporters
Electrodes to study membrane proteins
Steve Homans Conformational changes during β2-microglobulin amyloid assembly
Structural investigation of a fibronectin Type III -immunoglubulin domain tandem from A-band titin
Nigel Hooper Proteolysis and protein:protein interactions in neurodegenerative diseases
Lars Jeuken Electrodes to study membrane proteins
Peter Johnson Development of small- molecule tools to probe or inhibit biomolecules and their complexes
Studies on bacterial toxins
Andrew Macdonald Studies on bacterial toxins
Mike McPherson Molecular mechanisms of nutrient and drug uptake by cells
Structural and functional studies of copper amine oxidases
Adam Nelson Novel enzymes based on the N-acetyl neuraminic acid scaffold
Development of methods for the synthesis of skeletally-diverse alkaloid-like small molecules
Peter Olmsted Biophysical theory of lipid bilayers and proteins
Alex ONeill Development of small- molecule tools to probe or inhibit biomolecules and their complexes
Emanuele Paci Free-energy landscapes of proteins from simulation and experiment
Studies on bacterial toxins
Arwen Pearson Novel enzymes based on the N-acetyl neuraminic acid scaffold
Structural and functional studies of copper amine oxidases
Dynamic structural science: developing the tools to probe biological mechanism in atomic detail
Studies on bacterial toxins
An ADP-dependent kinase dependent upon N-phosphorylation of histidine
Mary Phillips-Jones Siamycin I directly inhibits the pheromone-stimulated autophosphorylation activity of the bacterial FsrC quorum sensor and phosphorylationdependent enzyme activities
Sheena Radford Biomolecular mass spectrometry
Conformational changes during β2-microglobulin amyloid assembly
Exploring protein folding energy landscapes
Revealing the structure of β2-microglobulin in amyloid fibrils by sitedirected spin labelling and chemical labelling
Neil Ranson The binding of bacteriophage MS2 to its target receptor
Studies on bacterial toxins
David Rowlands Viroporins and enveloped virus assembly as antiviral targets
The FMDV replication complex
Sarah S Staniland Biomimetic production of precise nanomagnetic particles using magnetic bacteria and their biomineralisation proteins
Peter Stockley Biomolecular mass spectrometry
The binding of bacteriophage MS2 to its target receptor
Development of smart nanoparticle-aptamer sensing technology
Nicola Stonehouse Biomolecular mass spectrometry
The FMDV replication complex
Targeting the functions of the Human Papilloma Virus 16 oncoproteins with RNA aptamers
Chris Thomas Defining the specificity of the Rep:PcrA interaction
Neil Thomson Single molecule microscopy with the AFM
John Trinick Nucleotide-dependent shape changes in the reverse direction molecular motor, myosin VI
Structural investigation of a fibronectin Type III -immunoglubulin domain tandem from A-band titin
Roman Tuma Pigment arrangement in chlorosomes from green filamentous bacterium Chloroflexus aurantiacus
Bruce Turnbull Studies on bacterial toxins
Stuart Warriner Development of methods for the synthesis of skeletally-diverse alkaloid-like small molecules
Proteomimetics as potential anticancer agents
Michael Webb Studies on bacterial toxins
An ADP-dependent kinase dependent upon N-phosphorylation of histidine
Adrian Whitehouse Identification of the ribonucleoprotein complex required for efficient viral RNA processing in oncogeneic herpesviruses
Andy Wilson Biomolecular mass spectrometry
Proteomimetics as potential anticancer agents
Dejian Zhou Development of smart nanoparticle-aptamer sensing technology
Astbury Seminars 2010 Download
Astbury Publications 2010 Download