... understanding life in molecular detail

Astbury Report 2012

INDEX TO THE 2012 REPORT
The full 2012 report can be downloaded as an 11.1MB pdf file here.
Individual reports can be downloaded as pdf files using the links below
Director's statement for 2012 Download
Alison Ashcroft Biomolecular mass spectrometry
Using ion mobility mass spectrometry to probe amyloid systems
Chemical and biochemical approaches to protein regulation and modification
Exploring protein-protein interaction inhibitors and peptide nanostructures
Stefan Auer Phase behaviour and transitions in complex biological systems
Steve Baldwin Dissecting the folding mechanism of the outer membrane protein PagP
Biomimetic production of precise nanomagnetic particles using magnetic bacteria and their biomineralisation proteins
John Barr Structure, function and evolution of the Crimean Congo hemorrhagic fever nucleocapsid protein
Paul Beales Interactions of nanoparticles and block copolymers with lipids in bilayer membranes
Alan Berry Improving on Nature: protein engineering and design
Robin Bon Label-free electrochemical detection of enzymatic activity using microarrays
David Brockwell Dissecting the folding mechanism of the outer membrane protein PagP
Extreme biophysics: a single molecule approach to explore proteins from extreme environments
Lorna Dougan Extreme biophysics: a single molecule approach to explore proteins from extreme environments
Structural examination of biologically-relevant solutions using neutron diffraction
James Duce A novel relationship between β-amyloid precursor protein and tau in neuronal iron trafficking
Thomas Edwards ATP-driven remodelling of the linker domain in the dynein motor
Structure, function and evolution of the Crimean Congo hemorrhagic fever nucleocapsid protein
Structural and mechanistic insights into the FusB family of fusidic acid resistance proteins
Exploring protein-protein interaction inhibitors and peptide nanostructures
Stephen Evans Biomimetic production of precise nanomagnetic particles using magnetic bacteria and their biomineralisation proteins
Colin Fishwick De novo design and virtual high-throughput screening to identify novel inhibitors of membrane proteins
Identification and optimisation of small molecule inhibitors of proteins for use as chemical probes or therapeutics
Richard Foster Identification and optimisation of small molecule inhibitors of proteins for use as chemical probes or therapeutics
Studies of small DNA tumour viruses that cause disease in humans
Stephen Griffin Studies of small DNA tumour viruses that cause disease in humans
Sarah Harris Using ion mobility mass spectrometry to probe amyloid systems
Mark Harris Studies on hepatitis C virus replication and pathogenesis
Eric Hewitt Disease-associated mutations abolish palmitoylation and membrane association of syntaxin 11 in natural killer cells
β2-microglobulin amyloid-lipid interactions
Nigel Hooper Prion protein in zinc metabolism and action of amyloid- oligomers in Alzheimerâ??s disease
Lars Jeuken The substrate of the quinol oxidase CymA is also a specific co-factor
Peter Knight ATP-driven remodelling of the linker domain in the dynein motor
Sergei Krivov Free energy landscape analysis of protein folding dynamics
Andrew Macdonald Studies of small DNA tumour viruses that cause disease in humans
Mike McPherson Using artificial binding proteins to inhibit protein-protein interactions
Stephen Muench Flexibility within the rotor and stator structures of the vacuolar ATPase
Adam Nelson Improving on Nature: protein engineering and design
Identification and optimisation of small molecule inhibitors of proteins for use as chemical probes or therapeutics
Development of tools and approaches to facilitate more systematic exploration of lead-like chemical space
Exploring protein-protein interaction inhibitors and peptide nanostructures
Alex ONeill Structural and mechanistic insights into the FusB family of fusidic acid resistance proteins
Emanuele Paci Flexibility within the rotor and stator structures of the vacuolar ATPase
Arwen Pearson Improving on Nature: protein engineering and design
Chemical and biochemical approaches to protein regulation and modification
Sheena Radford Dissecting the folding mechanism of the outer membrane protein PagP
β2-microglobulin amyloid-lipid interactions
Using ion mobility mass spectrometry to probe amyloid systems
RNA aptamers as research tools and diagnostic reagents in amyloid disease
Exploring protein-protein interaction inhibitors and peptide nanostructures
Peter Stockley RNA aptamers as research tools and diagnostic reagents in amyloid disease
Evidence that viral RNAs have evolved for efficient, two-stage packaging
Functional nanoparticle-bioconjugates for biosensing and biocatalysis
Chris Thomas Structure of a plasmid replication initiator protein: first example of the Rep_Trans family displays a novel fold
Neil Thomson Nucleic acid end labels for single molecule atomic force microscopy of DNA:RNA polymerase complexes
Darren Tomlinson Using artificial binding proteins to inhibit protein-protein interactions
John Trinick Flexibility within the rotor and stator structures of the vacuolar ATPase
NMR studies of the large super-repeats in titin
Roman Tuma Evidence that viral RNAs have evolved for efficient, two-stage packaging
Bruce Turnbull Protein modification reagents and binding studies on bacterial toxins
Chemical and biochemical approaches to protein regulation and modification
Stuart Warriner Development of tools and approaches to facilitate more systematic exploration of lead-like chemical space
Exploring protein-protein interaction inhibitors and peptide nanostructures
Michael Webb Protein modification reagents and binding studies on bacterial toxins
Chemical and biochemical approaches to protein regulation and modification
Functional nanoparticle-bioconjugates for biosensing and biocatalysis
Adrian Whitehouse Studies of small DNA tumour viruses that cause disease in humans
Using artificial binding proteins to inhibit protein-protein interactions
Identification of the ribonucleoprotein complex required for efficient viral RNA processing in oncogenic herpesviruses
Andy Wilson Using ion mobility mass spectrometry to probe amyloid systems
Exploring protein-protein interaction inhibitors and peptide nanostructures
Dejian Zhou Functional nanoparticle-bioconjugates for biosensing and biocatalysis
Astbury Seminars 2012 Download
Astbury Publications 2012 Download