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Astbury Report 2013

INDEX TO THE 2013 REPORT
The full 2013 report can be downloaded as an 6MB pdf file here.
Individual reports can be downloaded as pdf files using the links below
Director's statement for 2013 Download
Alison Ashcroft Biomolecular mass spectrometry
Using ion mobility mass spectrometry to probe amyloid formation
Nucleocapsid protein structures from orthobunyaviruses reveal insight into ribonucleoprotein architecture and RNA polymerization
Mechanistic insights into the material and cytotoxic properties of amyloid fibril polymorphs
Developing inhibitors of protein-protein interactions
Stefan Auer Phase behaviour and transitions in complex biological systems
John Barr Nucleocapsid protein structures from orthobunyaviruses reveal insight into ribonucleoprotein architecture and RNA polymerization
Identification of host cell ion channel modulators as new anti-viral targets
Paul Beales DNA-directed assembly of lipid nanodiscs into BioNanoStack architectures
Cytochrome c can permeabilize model mitochondrial membranes
Alan Berry Improving on Nature: protein engineering and design
Robin Bon Solid phase synthesis of functionalised SAM-forming alkanethiol-oligoethyleneglycols
David Brockwell Unravelling mechano-allostery using the atomic force microscope
In vitro studies of outer membrane protein assembly
Simon Connell Structural analysis of BTB-domain proteins implicated in human cancer
Kevin Critchley Solid phase synthesis of functionalised SAM-forming alkanethiol-oligoethyleneglycols
James Duce The involvement of β-amyloid precursor protein in neuronal iron homeostasis in dementia
Thomas Edwards Nucleocapsid protein structures from orthobunyaviruses reveal insight into ribonucleoprotein architecture and RNA polymerization
Developing inhibitors of protein-protein interactions
Colin Fishwick Optimising inhibitors for Toxoplasma gondii enoyl reductase
Identification and optimisation of small molecule as chemical probes or as therapeutics
Richard Foster Identification and optimisation of small molecule as chemical probes or as therapeutics
Structure-guided drug design targeting the release of hepatitis C virus particles
Studies of small DNA tumour viruses that cause disease in humans
Adrian Goldman The mechanism of a unique protozoan parasite primary ion pump
Stephen Griffin Structure-guided drug design targeting the release of hepatitis C virus particles
Studies of small DNA tumour viruses that cause disease in humans
Mark Harris Structure-guided drug design targeting the release of hepatitis C virus particles
Studies on hepatitis C virus replication and pathogenesis
Identification of host cell ion channel modulators as new anti-viral targets
Peter Henderson Ligand binding to a novel drug resistance protein measured using circular dichroism
Eric Hewitt Mechanistic insights into the material and cytotoxic properties of amyloid fibril polymorphs
Lars Jeuken Protein-protein interaction regulates the direction of catalysis and electron transfer in a redox enzyme complex
Sergei Krivov Understanding complex dynamics at atomistic resolution
Andrew Macdonald Studies of small DNA tumour viruses that cause disease in humans
Jamel Mankouri Identification of host cell ion channel modulators as new anti-viral targets
Kenneth McDowall Breaking dogmas: direct entry by RNase E and pervasive transcription
Stephen Muench Optimising inhibitors for Toxoplasma gondii enoyl reductase
Adam Nelson Improving on Nature: protein engineering and design
Identification and optimisation of small molecule as chemical probes or as therapeutics
Development of tools and approaches to facilitate more systematic exploration of lead-like chemical space
Developing inhibitors of protein-protein interactions
Alex ONeill Structural and mechanistic insights into the FusB family of fusidic acid resistance proteins
Emanuele Paci Understanding the mechanism and regulation of the Vacuolar ATPase
Arwen Pearson Improving on Nature: protein engineering and design
Structure-guided drug design targeting the release of hepatitis C virus particles
Developing new tools for time-resolved structural biology
Michelle Peckham Investigating how mutations in cardiac myosin cause heart and skeletal muscle disease
Sheena Radford Using ion mobility mass spectrometry to probe amyloid formation
Unravelling mechano-allostery using the atomic force microscope
In vitro studies of outer membrane protein assembly
Mechanistic insights into the material and cytotoxic properties of amyloid fibril polymorphs
Developing inhibitors of protein-protein interactions
Neil Ranson Nucleocapsid protein structures from orthobunyaviruses reveal insight into ribonucleoprotein architecture and RNA polymerization
David Rowlands Structure-guided drug design targeting the release of hepatitis C virus particles
Peter Stockley Mechanistic insights into the material and cytotoxic properties of amyloid fibril polymorphs
Nicola Stonehouse Nucleocapsid protein structures from orthobunyaviruses reveal insight into ribonucleoprotein architecture and RNA polymerization
Chris Thomas Alteration of the metal ion binding site of RepSTK1
Neil Thomson DNA secondary structure imaged by AFM
John Trinick Understanding the mechanism and regulation of the Vacuolar ATPase
Studies of the troponin complex in relaxed muscle thin filaments
Roman Tuma Structure and dynamics of hexameric helicases â?? from atomic details to single molecule biophysics
Bruce Turnbull Development of tools and approaches to facilitate more systematic exploration of lead-like chemical space
Methods for re-engineering bacterial toxins
Stuart Warriner Development of tools and approaches to facilitate more systematic exploration of lead-like chemical space
Developing new tools for time-resolved structural biology
Developing inhibitors of protein-protein interactions
Michael Webb Developing new tools for time-resolved structural biology
Methods for re-engineering bacterial toxins
Adrian Whitehouse Studies of small DNA tumour viruses that cause disease in humans
Identification of host cell ion channel modulators as new anti-viral targets
Identification of the ribonucleoprotein complex required for efficient viral RNA processing in oncogenic herpesviruses
Andy Wilson Developing inhibitors of protein-protein interactions
Stephanie Wright Structural analysis of BTB-domain proteins implicated in human cancer
Dejian Zhou A magnetic nanoparticle-enzyme based ultrasensitive diagnostic assay
Anastasia Zhuravleva Structural and mechanistic insights into the FusB family of fusidic acid resistance proteins
The relationship between conformational flexibility, landscape roughness, sequence variability and function for Hsp70 molecular chaperones
Astbury Seminars 2013 Download
Astbury Publications 2013 Download