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Astbury Report 2014
Astbury Report 2014
INDEX TO THE 2014 REPORT
The full 2014 report can be downloaded as a pdf file
here
.
Individual reports can be downloaded as pdf files using the links below
Director's statement for 2014
Download
Alison Ashcroft
♦
Biomolecular mass spectrometry
♦
Probing Bunyavirus N protein oligomerisation using mass spectrometry
♦
Novel methods for screening and classifying small molecule inhibitors of protein aggregation
♦
Modulation of biologically relevant processes using small molecules
Alison Baker
♦
Peroxisomal ABC transporters
♦
Plant Chemical Genetics
♦
Peroxisome protein import
Steve Baldwin
♦
Peroxisomal ABC transporters
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Phosphate Signalling and Transport
John Barr
♦
Probing Bunyavirus N protein oligomerisation using mass spectrometry
♦
The crystal structure of the M2-1 protein from human respiratory syncytial virus (HRSV) and its function as an anti-terminator
♦
Host cell ion channels as new anti-viral targets
Paul Beales
♦
Mechanistic insights into the role of lipid composition in the anticancer activity of an antimicrobial peptide
♦
β2-microglobulin amyloid fibrils disrupt membranes enriched in endosomal lipids and inhibit protein degradation by lysosomes
Alan Berry
♦
Peroxisome protein import
♦
Improving on Nature: protein engineering and design
Robin Bon
♦
Targeted contrast agents for imaging of inflammatory markers
Alex Breeze
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Monitoring New Delhi Metallo-ï¢-lactamase activity in live bacterial cells using NMR spectroscopy: new methods for antibacterials drug discovery
♦
Modulation of biologically relevant processes using small molecules
David Brockwell
♦
In vitro folding and remodelling of outer membrane proteins
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Physics of life in extreme environments
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Novel methods for screening and classifying small molecule inhibitors of protein aggregation
Stan Burgess
♦
Flexibility within the heads of muscle myosin-2 molecules
Joe Cockburn
♦
Cargo binding and regulation of kinesins
Simon Connell
♦
Mechanistic insights into the role of lipid composition in the anticancer activity of an antimicrobial peptide
Lorna Dougan
♦
Physics of life in extreme environments
James Duce
♦
The involvement of β-amyloid precursor protein proteolytic processing in neuronal iron homeostasis in dementia
Thomas Edwards
♦
Probing Bunyavirus N protein oligomerisation using mass spectrometry
♦
The crystal structure of the M2-1 protein from human respiratory syncytial virus (HRSV) and its function as an anti-terminator
♦
Modulation of biologically relevant processes using small molecules
Colin Fishwick
♦
The first small-molecule inhibitors of members of the ribonuclease E family
Richard Foster
♦
Targeted contrast agents for imaging of inflammatory markers
♦
Identification and optimisation of small molecule inhibitors as chemical tools
♦
Novel methods for screening and classifying small molecule inhibitors of protein aggregation
Stephen Griffin
♦
Viruses as combined anti-cancer and antiviral immunotherapies
Mark Harris
♦
Studies on hepatitis C virus replication and pathogenesis
♦
Host cell ion channels as new anti-viral targets
Sarah Harris
♦
Computational Biophysics
♦
Understanding the mechanism and regulation of the Vacuolar ATPase
Peter Henderson
♦
Kinetic dissection of the Na+-coupled binding of hydantoin to purified Mhp1
Eric Hewitt
♦
β2-microglobulin amyloid fibrils disrupt membranes enriched in endosomal lipids and inhibit protein degradation by lysosomes
Lars Jeuken
♦
Hybrid protein-nanoparticle layers for photovoltaics
Peter Knight
♦
Flexibility within the heads of muscle myosin-2 molecules
Sergei Krivov
♦
Fep1d: a script for the analysis of reaction coordinates
Andrew Macdonald
♦
Studies of small DNA tumour viruses that cause disease in humans
Jamel Mankouri
♦
Host cell ion channels as new anti-viral targets
Kenneth McDowall
♦
The first small-molecule inhibitors of members of the ribonuclease E family
♦
Direct entry by RNase E is a common pathway for the degradation and processing of RNA in Escherichia coli
Stephen Muench
♦
Phosphate Signalling and Transport
♦
Understanding the mechanism and regulation of the Vacuolar ATPase
Adam Nelson
♦
Improving on Nature: protein engineering and design
♦
Development of tools and approaches to facilitate the discovery of bioactive small molecules
♦
Modulation of biologically relevant processes using small molecules
Alex ONeill
♦
Structural and mechanistic insights into the FusB family of fusidic acid resistance proteins
Emanuele Paci
♦
In silico studies of proteins: folding, mechanics, dynamics and self-assembly
Michelle Peckham
♦
Cytoskeletal motors, muscle and single alpha helical domains, intriguing structural elements in proteins
Sheena Radford
♦
In vitro folding and remodelling of outer membrane proteins
♦
β2-microglobulin amyloid fibrils disrupt membranes enriched in endosomal lipids and inhibit protein degradation by lysosomes
♦
Targeting transient and lowly-populated species during amyloid assembly
♦
Novel methods for screening and classifying small molecule inhibitors of protein aggregation
♦
Modulation of biologically relevant processes using small molecules
Neil Ranson
♦
β2-microglobulin amyloid fibrils disrupt membranes enriched in endosomal lipids and inhibit protein degradation by lysosomes
Ryan Seipke
♦
Heterologous production of kitamycin by Escherichia coli
Peter Stockley
♦
Targeting transient and lowly-populated species during amyloid assembly
♦
Domain movements of the enhancer-dependent sigma factor drive DNA delivery into the RNA polymerase active site
Nicola Stonehouse
♦
Probing Bunyavirus N protein oligomerisation using mass spectrometry
♦
Studies on hepatitis C virus replication and pathogenesis
Darren Tomlinson
♦
Targeted contrast agents for imaging of inflammatory markers
John Trinick
♦
Understanding the mechanism and regulation of the Vacuolar ATPase
♦
Cryo-electron tomography of isolated muscle Z-discs
Roman Tuma
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Domain movements of the enhancer-dependent sigma factor drive DNA delivery into the RNA polymerase active site
Bruce Turnbull
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An engineered glycoprotein inhibitor of cholera toxin
Patricija van Oosten-Hawle
♦
Transcellular stress signalling: How proteotoxic stress is communicated between different tissues in C.elegans
Stuart Warriner
♦
Plant Chemical Genetics
♦
Peroxisome protein import
♦
Development of tools and approaches to facilitate the discovery of bioactive small molecules
♦
An engineered glycoprotein inhibitor of cholera toxin
♦
Modulation of biologically relevant processes using small molecules
Adrian Whitehouse
♦
Host cell ion channels as new anti-viral targets
Andy Wilson
♦
Modulation of biologically relevant processes using small molecules
Stephanie Wright
♦
Crystal structures of heterodimeric POZ domains
Anastasia Zhuravleva
♦
Structural and mechanistic insights into the FusB family of fusidic acid resistance proteins
♦
Molecular-level regulation of molecular chaperones
Astbury Seminars 2014
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Astbury Publications 2014
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