The Astbury Centre for Structural Molecular Biology

Members of the Asbury Centre.

As well as the members listed below the Astbury Centre also provides a vibrant supportive environment for Fellows. Details of our current Fellowships holders can be found by following this link - Current Fellows

A text list of staff with their research interests can be found at the bottom of the page

 


Facility Managers and Administrative Support

 


Visiting Members

John Findlay Structure and Mechanism of Action of Membrane Proteins, Receptors and Transport Systems

Steve Homans NMR Spectroscopy

Paul Ko Ferrigno Peptide aptamers-protein engineering-artificial antibodies-protein microarrays- cancer

Simon Phillips 

Mary Phillips-Jones Bacterial signalling and response to environmental change; bacterial sensing of antibiotics


Emeritus Members

Peter Johnson Molecular Modelling; Methods Development; Organic Synthesis

Peter Knowles Copper Oxidases; Free Radicals; Self-Assembly; Membranes

Tony North Macromolecular Structure

David Rowlands Structure and Replication Strategies of RNA Viruses


Members - text list

Alison Ashcroft Mass spectrometry, Ion Mobility Spectrometry, Biomolecular analysis

Stefan Auer Theoretical/Computational soft matter and biological physics

Steve Baldwin Membrane; Transport; Nucleoside; Protein structure

John Barr RNA virus nucleocapsid structure

Paul Beales Lipid membranes, Self-assembly, Nanomedicine, Synthetic Biology

Alan Berry Protein engineering; Directed evolution; Biocatalysis; Enzymology

Robin Bon Medicinal & Synthetic Organic Chemistry, Chemical Biology, Chemical Genetics.

David Brockwell Single Molecule Mechanical Unfolding of Proteins and their Complexes

Stan Burgess Cryoelectron microscopy, motor proteins, dynein structure and function

Simon Connell Atomic Force Microscopy, Lipid membranes

Kevin Critchley Self-assembly; Quantum dots, Nanowires, Self-assembled monolayers

Lorna Dougan Biophysics, Synthetic Biology, Liquids and Solutions Extreme Conditions

James Duce Neurobiology, metallomics, neurodegenerative disease

Thomas Edwards RNA Binding Proteins; X-ray Crystallography; Developmental Biology; Structural Molecular Biology

Stephen Evans Supported lipid membranes; Bio-templated nanowires and Nanostructured materials.

Colin Fishwick Medicinal chemistry, application of computer-aided methods in drug design and chemical biology

Richard Foster Medicinal chemistry, Chemical genetics, Virtual drug design, Fragment-based design

Stephen Griffin Hepatitis C virus, p7, ion channel, virus assembly

Mark Harris Hepatitis C virus, RNA protein interactions, replication, assembly

Sarah Harris Molecular dynamics simulation, theoretical biophysics

Peter Henderson Membrane Proteins, Sugar Transport, Antibiotic Resistance

Eric Hewitt Cellular Interactions with Amyloid and Molecular Immunology

Nigel Hooper Cell biology, proteolysis, Alzheimer

Lars Jeuken Bioinorganic chemistry; membrane biology; electron transfer; microbial fuel cells

Peter Johnson Molecular Modelling; Methods Development; Organic Synthesis

Peter Knight Structural Basis of Movement in Cells and Tissues

Sergei Krivov Protein folding, free energy landscapes, computational biology and biophysics.

Andrew MacDonald Structural studies on immune signaling proteins

Kenneth McDowall Macromolecular Interactions in RNA Processing and Decay

Mike McPherson Protein Engineering; Directed Evolution; Copper Oxidases; Protease Inhibitors; Functional Genomics and Proteomics

Stephen Muench Electron microscopy, X-ray crystallography, V-ATPase, rational drug design

Adam Nelson Directed evolution, chemical biology, chemical genetics, diversity-oriented synthesis

Alex O'Neill Bacterial resistance to antibiotics; biological characterization of novel antibacterial agents

Peter Olmsted Biophysics, protein dynamics and mechanics, lipid membrane physics, theory and computation

Emanuele Paci Computational Biology; Protein Folding; Molecular Dynamics

Arwen Pearson Structural Enzymology and Single Crystal Spectroscopy

Michelle Peckham Myosins, molecular motors, structure, imaging

Vas Ponnambalam Endothelium; Receptor-ligand function; Atherosclerosis; Cancer

Sheena Radford Protein folding, protein aggregation, amyloid disease

Neil Ranson Cryo-EM; Image Processing; Macromolecular structure

David Rowlands Structure and Replication Strategies of RNA Viruses

Sarah S Staniland Biomineralisation of magnetic nanoparticles in magnetic bacteria

Peter Stockley Self-assembling systems: Protein-nucleic acid regulatory complexes; molecular recognition; gene expression; bionanoscience

Nicola Stonehouse Virus, molecular interactions, vaccines, aptamers

Chris Thomas Plasmid Biology; Protein-DNA and Protein-Protein Interactions

Neil Thomson Biological Physics, Bionanotechnology, Atomic Force Microscopy (AFM)

Darren Tomlinson Artificial binding proteins, protein protein interactions, oncology, diagnostics

John Trinick Molecular Motors, Bioelasticity, Giant Proteins, Cryo-electron Microscopy

Roman Tuma Virus, self-assembly, molecular motors, optical tweezers

W. Bruce Turnbull Chemical Biology, Carbohydrate chemistry, Protein modification, Protein-ligand interactions

Stuart Warriner Automated Synthesis of Oligosaccharides, Chemical Synthesis

Michael Webb Enzymology, Bioorganic Chemistry, Protein modification, Calorimetry

David Westhead Bioinformatics, Computational Biology, Machine learning, Statistics

Adrian Whitehouse Viruses, cancer, KSHV, MCPyV

Andy Wilson Chemical Biology, Protein-Protein Interactions, Self-Assembly, Synthetic Chemistry

Stephanie Wright 

Dejian Zhou Nanoparticles, Biosensing, Nanomedicine, Chemical biology

Visiting Members

John Findlay Structure and Mechanism of Action of Membrane Proteins, Receptors and Transport Systems

Steve Homans NMR Spectroscopy

Paul Ko Ferrigno Peptide aptamers-protein engineering-artificial antibodies-protein microarrays- cancer

Simon Phillips 

Mary Phillips-Jones Bacterial signalling and response to environmental change; bacterial sensing of antibiotics

Emeritus Members

Peter Johnson Molecular Modelling; Methods Development; Organic Synthesis

Peter Knowles Copper Oxidases; Free Radicals; Self-Assembly; Membranes

Tony North Macromolecular Structure

David Rowlands Structure and Replication Strategies of RNA Viruses