... understanding life in molecular detail

Dr Rebecca Thompson

Cryo-electron microscopy, structural biology


My role is to pump prime research using the cryo-electron microscopy facilities at the Astbury BioStructure Laboratory. I can assist in project design, cryogenic sample preparation, the collection of preliminary data for grant applications, and data processing.   

Current major projects include:
  • Supporting the users to utilise cryo-EM in their scientific research
  • Single particle of macomolecular complexes to high resolution
  • Cryo-electron tomography of unique structures such as cells
  • Exploring the use of imaging techniques to complement cryo-EM
RebT.jpg

Senior CryoEM Support Scientist/Electron microscopy facility

Wellcome Trust PhD, University of Leeds, 2011-2015

Astbury 8.104
School of Molecular and Cellular Biology
0113 3434370
r.f.thompson@leeds.ac.uk

Selected Publications

  1. An introduction to sample preparation and imaging by cryo-electron microscopy for structural biology doi:10.1016/j.ymeth.2016.02.017

  2. The Asymmetric Structure of an Icosahedral Virus Bound to Its Receptor Suggests a Mechanism for Genome Release doi:10.1016/j.str.2013.05.012

  3. Mechanisms of assembly and genome packaging in an RNA virus revealed by high-resolution cryo-EM DOI: 10.1371/journal.pcbi.1004146

  4. New Structural insights nto the genome and minor capsid protein of BK polyomavirus using cryo-electron microscopy DOI: http://dx.doi.org/10.1016/j.str.2016.02.008