Dr Rebecca Thompson
Cryo-electron microscopy, structural biology
My role is to pump prime research using the cryo-electron microscopy facilities at the Astbury BioStructure Laboratory. I can assist in project design, cryogenic sample preparation, the collection of preliminary data for grant applications, and data processing.
Current major projects include:- Supporting the users to utilise cryo-EM in their scientific research
- Single particle of macomolecular complexes to high resolution
- Cryo-electron tomography of unique structures such as cells
- Exploring the use of imaging techniques to complement cryo-EM
Senior CryoEM Support Scientist/Electron microscopy facility
Wellcome Trust PhD, University of Leeds, 2011-2015
Astbury 8.104
School of Molecular and Cellular Biology
0113 343 3384
r.f.thompson@leeds.ac.uk
Selected Publications
An introduction to sample preparation and imaging by cryo-electron microscopy for structural biology doi:10.1016/j.ymeth.2016.02.017
The Asymmetric Structure of an Icosahedral Virus Bound to Its Receptor Suggests a Mechanism for Genome Release doi:10.1016/j.str.2013.05.012
Mechanisms of assembly and genome packaging in an RNA virus revealed by high-resolution cryo-EM DOI: 10.1371/journal.pcbi.1004146
New Structural insights nto the genome and minor capsid protein of BK polyomavirus using cryo-electron microscopy DOI: http://dx.doi.org/10.1016/j.str.2016.02.008